Marco Cammarata

Position:CNRS researcher (CR2)
Affiliation:CNRS / University of Rennes 1
Email (1):marco.cammarata@univ-rennes1.fr
Email (2):marco.cammarata.xray@gmail.com
researcherID:C-2322-2008



Observing and controlling state of matter

Protein structural transition


Different proteins react to the expousure of light that indeed may trigger structural relaxation. This has been used in the last 30 years to study how proteins relax to an impulsive perturbation. We are extending this technique to use the x-ray as direct structural probe. The first model systems we are studying are the "tertiary" relaxation of the Myoglobin and the quaternary transition of the human Hemoglobin

Selected Publications

reprints available here
  1. T. E. Glover, D.M. Fritz, M. Cammarata, T.K. Allison, S. Coh, J.M. Feldkamp, H.T. Lemke, D. Zhu, Y. Feng, R.N. Coffee, M. Fuchs, S. Ghimire, J. Chen, S. Shwartz, D.A. Reis, S.E. Harris & J.B. Hastings
    X-ray and optical wave mixing
    Nature: 488: 603-608 (2012); [Full Text/Abstract]
  2. M. Cammarata, M. Levantino, M. Wulff, A. Cupane
    "Unveiling the time scale of the R-T transition in human hemoglobin (with Cover and commentary from prof. Spiro)"
    Journal of Molecular Biology 400: 951-962 (2010) [Full Text/Abstract, journal issue web page]
  3. M. Cammarata, M. Levantino, F. Schotte, PA Anfinrud, F. Ewald, A. Cupane, M. Wulff, H. Ihee
    "Tracking the structural dynamics of proteins in solution using time-resolved wide-angle X-ray scattering"
    Nature Methods (5): 881-886, 2008. [Full Text/Abstract, journal issue web page]
  4. H. Ihee, M. Lorenc, T.K. Kim, Q.Y. Kong, M. Cammarata, J.H. Lee, S. Bratos, M. Wulff
    "Ultrafast x-ray diffraction of transient molecular structures in solution (with SOM and Perspective)"
    Science 309: 1223-1227 (2005)
  5. M. Cammarata, L. Eybert, F. Ewald, W. Reichenbach, M. Wulff, P. Anfinrud, F. Schotte, A. Plech, Q. Kong, M. Lorenc, B. Lindenau, J. Ribiger, and S. Polachowski
    "Chopper system for time resolved experiments with synchrotron radiation"
    Rev. Sci. Instrum. 80: 015101 (2009) [Full Text/Abstract]
  6. M. Cammarata, M. Lorenc, T.K. Kim, J.H. Lee, Q.Y. Kong, E. Pontecorvo, M. Lo Russo, G. Schirò, A. Cupane, M. Wulff and H. Ihee
    Impulsive solvent heating probed by picosecond x-ray diffraction J. Chem. Phys 124: 124504 (2006)
  7. M. Cammarata, M. Levantino, A. Cupane, A. Longo, A. Martorana, and F. Bruni
    "Structure and dynamics of water confined in silica hydrogels: X-ray scattering and dielectric spectroscopy studies"
    Eur. Phys. J. E12: S63-S66 (2003)